Peripheral blood smear
EBM Guidelines
Jul 3, 2024 • Latest change Nov 24, 2025
Table of contents
Extract
- Blood smear denotes microscopic examination of the peripheral blood, performed by
a physician on a peripheral blood film stained with the May–Grünwald–Giemsa (MGG) method. The examination is useful in situations where a disease causes a specific change in the morphology of blood cells.
- Blood cell morphology examination is carried out by a laboratory physician.
- Differential white cell count is performed by an automated blood cell counter. The blood cell counter alerts the staff about abnormal white blood cells / cell counts. The abnormal samples are used for a MGG-stained smear, which is microscopically examined by a laboratory technician. The findings can be commented on according to local guidelines, providing information partly similar to the morphological examination proper.
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