Mixed connective tissue disease (MCTD)
EBM Guidelines
Aug 21, 2022 • Latest change Aug 1, 2017
Table of contents
Extract
- Mixed connective tissue disease (MCTD) is a rare disorder, that shows features of rheumatoid arthritis, SLE, polymyositis and systemic sclerosis and that is characterized by anti-ribonucleoprotein antibodies in high titre.
- The clinical picture is variable and changes over time, often towards the clinical picture of systemic sclerosis.
- Most patients are women aged 30–40 years.
Search terms
Arthritis, ENA antibodies, Internal medicine, M35.1, M35.9, MCTD, Mixed Connective Tissue Disease, Mixed connective-tissue disease, Rheumatology